منابع مشابه
Double-hit and Triple-hit Lymphomas: New Perspectives for Their Classification
In 2016, an update on the classification of lymphoid neoplasm was published, and one of the modifications made focussed on B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt’s lymphoma, a term which has now been abandoned. This represented a very difficult disease in the diagnostic routine of pathologists. The new proposed term is high-...
متن کاملA leukemic presentation of a "triple-hit" lymphoma.
A 70-year-old man was diagnosed with stage IVA follicular lymphoma grade 1 in 2005. He initially received rituximab treatment in 2006. In the next 5 years, he was enrolled in several clinical trials including Zevalin radioimmunotherapy in 2007. He was recently admitted due to a new onset of gastrointestinal bleeding. At admission, a complete blood count showed mild anemia, severe thrombocytopen...
متن کاملGood HIT and bad HIT.
ne wo (E hospital ma O of the key issues for high-volume, high-risk rkplaces like hospital emergency departments Ds) is the struggle of conflicting aims. While nagers need information systems for data collection and storage, clinicians need efficient clinical documentation, data retrieval and order-entry systems that save time rather than steal it from the patient. The work of clinicians is aid...
متن کاملDoes the proliferation fraction help identify mature B cell lymphomas with double- and triple-hit translocations?
AIMS The entity 'B cell lymphoma, unclassifiable, with features intermediate between diffuse large B cell lymphoma (DLBCL) and Burkitt lymphoma (BL)' refers to B cell neoplasms that share overlapping characteristics of BL and DLBCL. A subset of these 'grey-zone lymphomas' possesses C-MYC and IGH translocations but, in addition, contains additional rearrangements of BCL2 and/or BCL6 genes. The a...
متن کاملHit discovery and hit-to-lead approaches.
Hit discovery technologies range from traditional high-throughput screening to affinity selection of large libraries, fragment-based techniques and computer-aided de novo design, many of which have been extensively reviewed. Development of quality leads using hit confirmation and hit-to-lead approaches present their own challenges, depending on the hit discovery method used to identify the init...
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ژورنال
عنوان ژورنال: Lung India
سال: 2015
ISSN: 0970-2113
DOI: 10.4103/0970-2113.164165